Changes in Female Sex Hormones in Patients with Intentional Drug and Chemical Poisoning

Authors

  • Mehri Jamilian Department of Obstetrics and Gynecology, Arak University of Medical Sciences, Arak, Iran.
  • Saadat Torabian Department of Community Medicine, Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Saeed Afzali Department of Forensic Medicine and Clinical Toxicology, Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Seyed Kazem Taheri Department of Forensic Medicine and Clinical Toxicology, Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, Iran.
Abstract:

Background: Hormonal changes as a factor influencing the emotional state of women have an important role in the incidence of suicide. The aim of this study is to investigate changes in FSH-LH, Estrogen, and Progesterone hormones in women attempting suicide by drugs and chemicals. Methods: In this cross-sectional study, women of reproductive diagnosed with drug and chemical poisoning who were hospitalized in Farshchian Hospital, Hamadan, Iran, were assessed regarding LH, FSH estrogen and progesterone hormones over a period of six months in 2011. Overall, 80 patients were studied with regard to the inclusion and exclusion criteria. Results: The highest rate of suicide was in the age range of 14-25 years (47 patients, 60.1%). A significant relationship was observed among the blood levels of hormones FSH, LH, progesterone, and estrogen. The association of hormone levels and LMP and attempted suicide was significant. The LH level was significantly lower in patients with substance abuse. The estrogen level was significantly lower in patients with the history of self-injury. Most patients (67.5%) were in the follicular phase which was statistically significant. Conclusion: According to the obtained results, there was a significant relationship between the levels of different hormones. The significant relationship was positive in some cases but negative in other.

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Journal title

volume 7  issue None

pages  793- 797

publication date 2013-04

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